Writing a novel can be quite difficult, there is no magic formula for novel-writing. Every novel demands its own structure, its own pace, its own way of looking at the world.
It can cause you utter frustration and despair, however it can also be one of the most thrillingly creative thing a person can do.
With regards to the characters. There has to be someone in the centre of the action (protagonist). Generally, this will be someone that your readers will end up rooting for, not matter how flawed the character may be. They must be flawed to make them realistic. One of my favourite characters is Dexter Morgan and Forensic Blood Splatter Analyst by day and a serial killer by night, even though I completely disagree with what he does I still do not want him to get caught. Every great novel is character-driven; your protagonist must be a character worth caring about.
I think you may have to look at your characters and decide which one will take the centre of your novel, 20 lead roles could leave your readers confused. In reflection I am sure that one character will stand out as the protagonist, and the other 19 characters interact with them helping to build and mould the story.
When you begin your novel, it is less important to know where it is going than it is to know who your protagonist is. It is easy to start writing without a thought of what events will occur, but it is almost impossible to start a story without considering who will be at the centre of those events.
Just remember that your characters create the plot, it is their natural motivations and desires which will drive the conflict in your novel, and their reactions which will shape the events in your story.
Or another way of thinking about it is like the solar system, your main character is the sun, without it no other element of your story can survive.